Haematological parameters are good indicators of the physiological status of animals and useful in understanding the
relationship of blood to the environment. This study was carried out to compare the fasting levels of blood glucose and
haematological parameters (Red blood cell count, Packed cell volume, Haemoglobin concentration, White blood cell count,
Platelet count, and differential White blood cell counts) in Wistar rats, Rattus norvegicus and the common African toad, Bufo
regularis. Ten rats and ten toads were used in the study. The animals were divided into two groups. Group I consists of 10 rats
while Group II consists of 10 toads. The animals were fasted overnight before blood samples were collected for the
determination of blood glucose and blood parameters. The blood glucose was determined using modified glucose oxidase
method while the blood parameters were determined using standard laboratory techniques. The results of the study showed that
the fasting blood glucose level in rats was significantly higher than that of toad. The fasting levels of blood parameters, packed
cell volume, red blood cell counts, haemoglobin concentration in the toad were significantly lower than those of rats while the
white blood cell counts of the toads were significantly higher compared with the rats. There were no significant differences in
neutrophil, monocyte, eosinophil and lymphocyte counts of rats when compared with those of the toad.